Chloroquine-diphosphate/ciprofloxacin/meropenem

Prophylactic Effect of Chloroquine and Hydroxy chloroquine in COVID-19 Treatment

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety.Hydroxychloroquine (HCQ) is an anti-malaria drug; its antiviral properties are controversial,and some in vitr...

Chloroquine diphosphate

Human toxicity Chloroquine is a potentially fatal poisoning, often characterized by rapid deterioration. Features of toxicity may develop within 1 to 2 h, and death may occur abruptly, generally from myocardial depression and dysrhythmia. Symptoms at an acute overdose are as following: hyperexcitability, agitation, seizures, cerebral edema, ventricular dysrhythmia, hypotension, shock, cardiac a...

Chloroquine myopathy.

[Chloroquine retinopathy].

Chloroquine Retinopathy refers to the changes seen in the retina of patients due to long term use of chloroquine. The late presentation, classically described as bull’s eye maculopathy, is preceded by a number of subtle changes. With the advent of new investigation modalities and regular screening, it is possible to prevent irreversible retinal damage due to this important and widely used drug....

Variation of the Chloroquine Resistance Transporter (Crt) Gene in Chloroquine-Resistant and Chloroquine-Sensitive Plasmodium berghei

Background: The emergence and spread of chloroquine resistant Plasmodium falciparum in the world stimulated some investigators to consider different aspects of chloroquine resistance in human and rodent Plasmodia. Using animal Plasmodia, particularly primate and rodent Plasmodia can be useful model for human Plasmodia studies. In this study we have tried to consider and compare the sequence of ...